Effect of defects on thermal denaturation of DNA oligomers.

نویسندگان

  • N Singh
  • Y Singh
چکیده

Effect of defects on the melting profile of short heterogeneous DNA chains is calculated using the Peyrard-Bishop Hamiltonian. On-site potential on a defect site is represented by a potential that has only a short-range repulsion and a flat part without well of the Morse potential. Stacking energy between two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.

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عنوان ژورنال:
  • Physical review. E, Statistical, nonlinear, and soft matter physics

دوره 64 4 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2001